Academic Resources

Academic CBD Research

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Anxiety

Recent studies have pointed to the potential benefits of CBD for treating anxiety.

The National Institute on Drug Abuse (NIDA) says that CBD has been shown to alleviate generalized anxiety disorder (GAD) in a preclinical study.

More research suggests that CBD is beneficial for other forms of anxiety, such as social anxiety disorder (SAD) and post-traumatic stress disorder (PTSD). It may help treat anxiety-induced insomnia as well.

Multiple recent studies have shown that CBD can help with PTSD symptoms. These studies have looked at CBD as both a standalone PTSD treatment as well as a supplement to traditional treatments like medication and cognitive behavioral therapy (CBT).

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Sleep

With a calming effect for the central nervous system, adults in the study who used CBD were able to alleviate anxiety and sleep during the first month of the study.

CBD is found helpful for sleep, due to its ability to alleviate conditions that interfere with sleep, by calming the central nervous system.
CBD is believed to improve sleep directly, even if you the person does not suffer from anxiety, stress, or chronic pain, by interacting with receptors in the body, including receptors that govern the body’s sleep and wake cycle.

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Pain

CBD oil has been commonly used as a natural approach for the relief of pain. Either chronic or acute pain, generated from different reasons, CBD seems to be beneficial in alleviation of it. Research suggests that CBD may have pain-relieving effects for neuropathic pain, inflammation-induced pain, among other pain-related conditions.

Studies have shown that CBD’s ability to affect chronic pain, is by impacting endocannabinoid receptor activity, reducing inflammation and interacting with neurotransmitters
A study in a rat model shows that CBD injections caused reduction of pain, in response to surgical incision. Another rat study found that oral CBD treatment significantly reduced sciatic nerve pain and inflammation.

Several human studies have found that a combination of CBD and THC is effective in treating pain related to multiple sclerosis.

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Acne Treatment

Recent studies have shown evidence that CBD oil is helpful with treating acne due to its anti-inflammatory properties and ability to reduce sebum production.

In an in vitro study, CBD oil succeeded in preventing sebaceous gland cells from secreting excessive sebum. It also exerted anti-inflammatory actions and prevented the activation of “pro-acne” agents like inflammatory cytokines

Similar findings were achieved by another study, which concluded that CBD may be an efficient and safe way to reduce acne, due to its anti-inflammatory qualities.

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Neuroprotective Properties

Researchers believe that CBD’s ability to act on brain signaling systems may be beneficial for treatment of neurological disorders.

Neurological disorders like epilepsy and multiple sclerosis are of the most studied for treatment with CBD. Although research in this area is still at its early stages, results are promising.

Sativex (an oral spray consisting of CBD and THC) has been established as a safe and effective way to reduce muscle spasticity in people who suffer from multiple sclerosis. Sativex was proven to reduce spasms in 75% of 276 people with multiple sclerosis who were experiencing medication-resistant muscle spasticity.

In another study, CBD was found effective in reducing seizures in people suffering from epilepsy.

An additional study proved that CBD oil significantly reduced seizure activity in children with Dravet syndrome, a complex childhood epilepsy disorder, compared to a placebo.
CBD has also been researched for its potential effectiveness in treating several other neurological diseases, like Parkinson’s disease, Alzheimer’s disease and more.

Known side-effects of CBD

  • Anxiety
  • Changes in appetite
  • Changes in mood
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Nausea
  • Vomiting